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First (Given) Name:
Ana
Middle Name:
Last (Family) Name:
Ramos
Date Joined:
07/14/2008
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Hello

My name is Ana and I am translator and interpreter. I am 23 years old, I am spanish and I am currently living in Spain. My source languages are english,german and galician and my target language is spanish. I am specialized in scientific texts from english into spanish and german into spanish, but also in economic and legal texts for the same language combinations. I have lived one year in Germany within the ERASMUS program (Universität Hildesheim) and I have FIRST certificate in englis
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Article Title: Peptides
Date Created:
07/14/2008
Date Updated:
07/14/2008
Language:
English
Category:
Translation
TranslatorPub.Com Rank:
10
Views:
2552
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0
Ratings:
2, Average Rating: 9 (10 Max)
Text:
When viruses infect human cells they exploit the cell´s ribosomes to synthesize viral proteins, which are therefore present in the cytosol before being assembled into viral particles. In response, the infected cell uses its normal processes of breakdown and turnover of cellular proteins to degrade some of the viral proteins into peptides that can be bound by MHC class I molecules and presented to CD8 Tcells. Proteins in the cytosol are degraded by a large barrel-shaped protein complex called the proteasome, which has several different protease activities.


Cuando los virus infectan las células humanas aprovechan los ribosomas de la célula para sintetizar las proteínas víricas, por lo que estas están presentes en el citosol antes de formar partículas víricas. Como respuesta a ello, la célula infectada utiliza los procesos comunes de descomposición y reemplazamiento de proteínas celulares para degradar algunas proteínas víricas en péptidos que puedan unirse a moléculas de MHC de clase I y ser presentados a los linfocitos T CD8.
En el citosol, las proteínas se degradan mediante un gran complejo proteico de forma cilíndrica denominado proteasoma, el cual lleva a cabo diferentes actividades de peptidasa.
 
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